Peyronie’s disease causes scar tissue in the penis that can lead to curvature, pain and/or difficulty with erections. A range of treatments is available, depending on whether it is in the acute or chronic phase.
CONDITIONS
Peyronie’s Disease

Symptoms
• Pain with erection
• Curvature or deformity of the penis
• A palpable lump or plaque
• Loss of length


How We Diagnose Peyronie’s Disease
• Clinical history and examination
• Assessment of the plaque and curvature, sometimes with photographs or ultrasound
• Review of erectile function

How We Treat Peyronie’s Disease
• Acute phase (can last 6–12 months)
• Oral medications, including PDE5 inhibitors such as tadalafil, to support erectile function during the active phase
• Traction therapy
• Intra-lesional injections – Xiaflex is no longer available in Australia
• Chronic phase
• Penile plication – surgery to straighten the penis for minor curvature
• Excision and grafting – surgery for more severe curvature
• Penile implant – can be used to help curvature and treat erectile dysfunction
